ROSARIO ADELAIDA MUÑOZ CLARES

Entidad: Facultad de Química, UNAM

Telefono: 56223718

Email: clares@unam.mx

Url:

Departamento: --

Línea de trabajo y/o generación del conocimiento: Química de Alimentos y Biotecnología


Tesis Doctorado

TesisAlumno

Tesis Maestría

TesisAlumno
CLONACION, SOBREEXPRESION Y CARACTERIZACION CINETICA DE LA ENZIMA ALDEHIDO DESHIDROGENASA PA5312 DE PSEUDOMONAS AERUGINOSA YUDY VANESA CARDONA CARDONA
Clonación, sobreeexpresión y caracterización cinética de la enzima aldehído deshidrogenasa PA2125 de Pseudomonas aeruginosa CARLOS ALBERTO RUEDA SANABRIA

Publicaciones:

  • Amino acid residues that affect the basicity of the catalytic glutamate of the hydrolytic aldehyde dehydrogenases
    Muñoz-Clares, Rosario A.,González-Segura, Lilian,Riveros-Rosas, Héctor,Julián-Sánchez, Adriana
    Chemico-Biological Interactions 2015, (234), , 45 - 58
    doi: 10.1016/j.cbi.2015.01.019
  • Residues that influence coenzyme preference in the aldehyde dehydrogenases
    González-Segura, Lilian,Riveros-Rosas, Héctor,Julián-Sánchez, Adriana,Muñoz-Clares, Rosario A.
    Chemico-Biological Interactions 2015, (234), , 59 - 74
    doi: 10.1016/j.cbi.2014.12.039
  • Exploring the evolutionary route of the acquisition of betaine aldehyde dehydrogenase activity by plant ALDH10 enzymes: implications for the synthesis of the osmoprotectant glycine betaine
    Muñoz-Clares, Rosario A,Riveros-Rosas, Héctor,Garza-Ramos, Georgina,González-Segura, Lilian,Mújica-J
    BMC Plant Biol 2014, (14), 1, 149 -
    doi: 10.1186/1471-2229-14-149
  • Potential monovalent cation-binding sites in aldehyde dehydrogenases
    González-Segura, Lilian,Riveros-Rosas, Héctor,Díaz-Sánchez, Ángel G.,Julián-Sánchez, Adriana,Muñoz-C
    Chemico-Biological Interactions 2013, (202), 1-3, 41 - 50
    doi: 10.1016/j.cbi.2012.12.007
  • Structural determinants of substrate specificity in aldehyde dehydrogenases
    Riveros-Rosas, Héctor,González-Segura, Lilian,Julián-Sánchez, Adriana,Díaz-Sánchez, Ángel G.,Muñoz-C
    Chemico-Biological Interactions 2013, (202), 1-3, 51 - 61
    doi: 10.1016/j.cbi.2012.11.015
  • Potassium and Ionic Strength Effects on the Conformational and Thermal Stability of Two Aldehyde Dehydrogenases Reveal Structural and Functional Roles of K+-Binding Sites
    Garza-Ramos, Georgina,Mújica-Jiménez, Carlos,Muñoz-Clares, Rosario A.
    PLoS ONE 2013, (8), 1, e54899 -
    doi: 10.1371/journal.pone.0054899
  • Amino Acid Residues Critical for the Specificity for Betaine Aldehyde of the Plant ALDH10 Isoenzyme Involved in the Synthesis of Glycine Betaine
    Diaz-Sanchez, A. G.,Gonzalez-Segura, L.,Mujica-Jimenez, C.,Rudino-Pinera, E.,Montiel, C.,Martinez-Ca
    PLANT PHYSIOLOGY 2012, (158), 4, 1570 - 1582
    doi: 10.1104/pp.112.194514
  • Allosteric regulation of the photosynthetic C4 isoenzyme of phosphoenolpyruvate carboxylase: A comparative study between enzymes from monocot and dicot plants
    Rodrigo Güémez-Toro ; Carlos Mújica-Jiménez ; Rosario A. Muñoz-Clares ;
    Journal of the Mexican Chemical Society 2012, (56), 1, 58 - 56
    doi:
  • Novel NADPH–cysteine covalent adduct found in the active site of an aldehyde dehydrogenase
    Díaz-Sánchez, Ángel G.,González-Segura, Lilian,Rudiño-Piñera, Enrique,Lira-Rocha, Alfonso,Torres-Lar
    Biochem. J. 2011, (439), 3, 443 - 455
    doi: 10.1042/BJ20110376
  • Crystallographic evidence for active-site dynamics in the hydrolytic aldehyde dehydrogenases. Implications for the deacylation step of the catalyzed reaction
    Muñoz-Clares, Rosario A.,González-Segura, Lilian,Díaz-Sánchez, Ángel G.
    Chemico-Biological Interactions 2011, (191), 1-3, 137 - 146
    doi: 10.1016/j.cbi.2010.12.024
  • The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial
    Zaldívar-Machorro, Víctor J.,López-Ortiz, Manuel,Demare, Patricia,Regla, Ignacio,Muñoz-Clares, Rosar
    Biochimie 2011, (93), 2, 286 - 295
    doi: 10.1016/j.biochi.2010.09.022
  • Kinetic and structural features of betaine aldehyde dehydrogenases: Mechanistic and regulatory implications
    Muñoz-Clares, Rosario A.,Díaz-Sánchez, Ángel G.,González-Segura, Lilian,Montiel, Carmina
    Archives of Biochemistry and Biophysics 2010, (493), 1, 71 - 81
    doi: 10.1016/j.abb.2009.09.006

Patentes: